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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 141645Generated: October 31, 2026

Tetrahydrofuran → 2-(2-Chlorophenylamino)-3,4-difluoro-6-trimethylsilanylethynylbenzoic acid methyl ester

https://huagongshe.com/reaction/141645

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant6-Bromo-2-(2-chlorophenylamino)-3,4-difluorobenzoic acid methyl esterHCID 86598592—
Product2-(2-Chlorophenylamino)-3,4-difluoro-6-trimethylsilanylethynylbenzoic acid methyl esterHCID 86598593—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-324422d3c8894b53b0883332ab707a6e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)