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HRID1416572

反应详情

EQUATION

反应方程式

HRID 1416572 的结构方程式

REACTANTS

反应物

2
结构：NC1CCc2ccccc21
HCID123445

1-Aminoindan

C9H11N

结构：CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Cl)cc1
HCID2735528

4-(Dipropylsulfamoyl)benzoyl chloride

C13H18ClNO3S

PRODUCTS

生成物

1
结构：CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC2CCc3ccccc32)cc1
HCID18627820

未命名化合物

收率 63%

PROCEDURE

实验过程

The title compound was prepared in 63% yield from (rac)-1-aminoindan (10.0 g, 75.2 mmole) and 4-(di-n-propylsulfamoyl) benzoyl chloride (16.3 g, 53.6 mmole, prepared from probenecid and SOCl2) via a procedure analogous to that described in Ex. 46, followed by crystallization from hexane:EtOAc, mp: 124-5° C.

WORKUP

后处理

  1. custom46, followed by crystallization from hexane