Succinyl chloride → N,N'-Bis-((R)-1-indanyl)succinamide

HRID 1416574Notes

Reaction equation

HRID 1416574 reaction equation
[NH2:1][C@H:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[C:11](Cl)(=[O:17])[CH2:12][CH2:13][C:14](Cl)=[O:15]>>[C@H:2]1([NH:1][C:11](=[O:17])[CH2:12][CH2:13][C:14]([NH:1][C@H:2]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH2:4][CH2:3]2)=[O:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 10970Succinyl chlorideHCID 2733933(R)-(-)-1-Aminoindan

Product 1

HCID 53712777N,N'-Bis-((R)-1-indanyl)succinamide

Procedure

This was prepared by the same procedure as in Example 73 starting from (R)-1-aminoindan (8.02 g, 60 mmole) and succinoyl chloride (2.32 g, 14 mmole), to give the white product, (1.30 g, 26.7%). Melting point: 266-9° C.

Workup

  1. customto give the white product, (1.30 g, 26.7%)

Sources & evidence

ORD record
ord-2c030952cbd5487ca4cba3b6747a8bbf
Source dataset
uspto-grants-1999_06
Patent number
US05914349

Reaction notes

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