Methanol → 2-Methyl bicyclo(2.2.1)hept-5-ene-2,3-dicarboxylate
Reaction equation
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH:3]1[C:8]([O:10][C:11](=[O:12])[CH:2]21)=[O:9].[CH3:13][OH:14]>>[CH3:13][O:14][C:8]([CH:3]1[CH:2]([C:11]([OH:10])=[O:12])[CH:1]2[CH2:7][CH:4]1[CH:5]=[CH:6]2)=[O:9]Participants
3
Procedure
The same procedure as that of process (I) of Example 1 was conducted to obtain a 50% by weight methanol solution of (A1). In the same manner, to a 1 liter flask were added 24.00 g of 5-norbornene-2,3-dicarboxylic anhydride and 33.37 g of methanol, and the resulting mixture was stirred under reflux in a water bath kept at 90° C. Ninety minutes after initiation of the stirring, solid components disappeared, 3 hours after, the temperature was lowered to room temperature to obtain a 50% by weight methanol solution of 5-norbornene-2,3-dicarboxylic monomethyl ester.
Workup
- temperatureunder reflux in a water bath
- customkept at 90° C
- customwas lowered to room temperature
Sources & evidence
- ORD record
- ord-e3f350cb578a49e8bf455b47fa780862
- Source dataset
- uspto-grants-1999_06
- Patent number
- US05914385
Reaction notes
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