Methanol → Monomethyl maleate

HRID 1416588Notes

Reaction equation

HRID 1416588 reaction equation
[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH:3]=[CH:2]1.[CH3:8][OH:9]>>[CH3:8][O:9][C:4](=[O:5])/[CH:3]=[CH:2]\[C:1]([OH:6])=[O:7]

Participants

3

Reactant 2

HCID 887Methanol2×HCID 7923Maleic Anhydride

Product 1

HCID 5354456Monomethyl maleate

Procedure

The same procedure as that of process (I) of Example 1 was conducted to obtain a 50% by weight methanol solution of (A1). In the same manner, to a 1 liter flask were added 24.00 g of maleic anhydride and 39.68 g of methanol, and the resulting mixture was stirred under reflux in a water bath kept at 90° C. Thirty minutes after initiation of the stirring, solid components disappeared, 3 hours after, the temperature was lowered to room temperature to obtain a 50% by weight methanol solution of maleic monomethyl ester.

Workup

  1. temperatureunder reflux in a water bath
  2. customkept at 90° C
  3. customwas lowered to room temperature

Sources & evidence

ORD record
ord-cc36d2f1e923404c8fb8aef00087bf94
Source dataset
uspto-grants-1999_06
Patent number
US05914385

Reaction notes

Loading…