Ammonia → HCID 54335638, compound

HRID 1416604Notes

Reaction equation

HRID 1416604 reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([O:8][CH2:9][C@@H:10]2[CH2:14][CH2:13][CH2:12][NH:11]2)=[CH:4][CH:3]=1.N.[CH:16](Cl)(Cl)Cl>>[CH3:1][C:2]1[N:7]=[CH:6][C:5]([O:8][CH2:9][C@H:10]2[CH2:14][CH2:13][CH2:12][N:11]2[CH3:16])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 6212ChloroformHCID 42633104HCID 42633104, compound

Product 1

HCID 54335638HCID 54335638, compound

Procedure

The title compound was prepared from the compound of step 36a in a manner similar to compound 18b TLC Rf =0.17 (10%MeOHI/CHCl3). MS (DCI/NH3) and 1H NMR (CDCl3,300 MHz) are similar to the compound of step 18b

Sources & evidence

ORD record
ord-c33b25dbc52c4dd0ac6302b2ef72cca8
Source dataset
uspto-grants-1999_06
Patent number
US05914328

Reaction notes

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