HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 21309664, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 2-Methyl-5-hydroxypyridine | HCID 14275 | — |
| Reactant | Diethyl azodicarboxylate | HCID 5462977 | — |
| Reactant | tert-butyl (2S)-2-(hydroxymethyl)azetidine-1-carboxylate | HCID 10511797 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21309664 | HCID 21309664 | — |
Reaction Steps
A 3.74 g (20 mmol) sample of 1-t-butyloxycarbonyl-2-(S)-azetidinemethanol, prepared as in Example 7b above, and 3.27 g (30 mmol) of 2-methyl-5hydroxypyridine were reacted with triphenylphosphine and DEAD (30 mmol each) in 100 mL of THF according to the procedure of Example 14a, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05914328 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-d5c76618f1444212a45260516687a3d0 |
| Source note | uspto-grants-1999_06 |