Sodium Hydroxide → HCID 67585000, compound

HRID 1416656Notes

Reaction equation

HRID 1416656 reaction equation
[ClH:1].Cl.C[O:4][C:5]([C:7]1[CH:8]=[C:9]([O:13][CH2:14][C@@H:15]2[CH2:19][CH2:18][CH2:17][N:16]2[CH3:20])[CH:10]=[N:11][CH:12]=1)=[O:6].[OH-].[Na+]>>[ClH:1].[ClH:1].[CH3:20][N:16]1[CH2:17][CH2:18][CH2:19][C@H:15]1[CH2:14][O:13][C:9]1[CH:10]=[N:11][CH:12]=[C:7]([C:5]([OH:6])=[O:4])[CH:8]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 69831043HCID 69831043, compound

Product 1

HCID 67585000HCID 67585000, compound

Procedure

A sample of the compound from Example 100 above is hydrolyzed with 1N NaOH according to standard methods. The product is purified by chromatography on silica gel and converted into the title compound by treatment with HCl in ether according to Example 14c.

Workup

  1. customThe product is purified by chromatography on silica gel

Sources & evidence

ORD record
ord-40680e02a3a4453587b3a2fe4c57d32f
Source dataset
uspto-grants-1999_06
Patent number
US05914328

Reaction notes

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