Hydrochloric Acid → 5-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid bis-(2-phenoxy-ethyl) ester hydrochloride salt

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The title compound was prepared from 5-{2-[2-(3-chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid and 2-phenoxyethanol according to the procedure of Example 1 as an off-white gummy solid; 1H NMR (300 MHz, CDCl3): δ 1.23-1.40 (brs, 3H), 2.70-2.90 (brm, 1H), 3.05-3.30 (brm, 2H), 3.31-3.52 (brm, 2H), 4.12 (t, J=4.4 Hz, 4H), 4.57 (t, J=4.8 Hz, 4H), 5.38-5.60 (brs, 2H), 6.70-7.0 (complexm, 10H), 7.15-7.47 (complex m, 7H), 8.60-8.80 (brs, 1H), 9.90-10.20 (brs, 1H).; MS (ES) m/z (relative intensity): 662 (M+ -HCl, (100), 594 (20), 498 (35).

Provenance & Evidence