Cyclopentanol → HCID 9915764, compound

Participants

Reaction Steps

The title compound was prepared from 5-{2-[2-(3-chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid and cyclopentanol as a yellow gum according to the procedure of Example 1, leaving out the final HCl(g) /Et2O hydrochloride salt forming step: 1H NMR (300 MHz, CDCl3): δ 1.07 (d, J=6.2 Hz, 3H), 1.50-2.00 (complex m, 16H), 2.52-2.70 (complex m, 3H), 2.85-2.95 (m, 2H), 4.55-4.65 (m, 1H), 5.29-5.38 (m, 2H), 6.65-6.72 (m, 1H), 6.76 (s, 1H), 6.84 (d, J=8.0 Hz, 1H), 7.18-7.30 (m, 3H), 7.37 (s, 1H); MS (ES) m/z (relative intensity): 558 (M+, 100), 518 (10), 490 (20).

Provenance & Evidence