Hydrochloric Acid → HCID 9808589, compound

Participants

Reaction Steps

The title compound was prepared from 5-{2-[2-(3-chloro-phenyl)-2-hydroxy-ethylarnino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid and 3,3-dimethylbutanol according to the procedure of Example 30 as a white foam (HCl salt); 1H NMR (CDCl3) δ 0.90 (s, 18H), 1.33 (bs, 3H), 1.62 (t, J=7.4 Hz, 4H), 2.80 (bs, 1H), 3.18 (bs, 2H), 3.48 (bs, 2H), 4.35 (t, J=7.4 Hz, 4H), 5.45 (bs, 1H), 6.80 (m, 3 H), 7.26 (m, 2H), 7.43 (s, 1H), 8.70 (bs, 1H), 10.10 (bs, 1H); IR (KBr): 1765 cm-1 (C=O); MS (CI) m/z 590 (MH+); [α]D5 -24° (c, 1.0, CHCl3). Anal. Calcd. for C32H44ClNO7 ·HCl: C, 61.34; H, 7.08; N, 2.24; Cl, 11.32. Found: C, 60.79; H, 7.46; N, 2.09; Cl, 11.95.

Provenance & Evidence