Hydrochloric Acid → HCID 53692608, compound

Participants

Reaction Steps

The title compound was prepared from 5-{2-[2-(3-chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-benzo[1,3]dioxole-2,2-dicarboxylic acid and 2-cyclopentylethanol according to the procedure of Example 30 as an amber gum (HCl salt); 1H NMR (CDCl3) δ 1.32 (d, J=6.3 Hz, 3H), 1.60 (m, 20H), 2.80 (m, 1H), 2.90 (m, 2H), 3.15 (m, 1H), 3.20 (m, 1H), 3.48 (m, 2H), 4.30 (t, J=6.9 Hz, 4H), 5.50 (bd, 1 H), 6.80 (m, 3H), 7.25 (m, 2H), 7.43 (s, 1H), 8.70 (bs, 1H), 10.10 (bs, 1H); IR (KBr): 1765 cm-1 (C=O); MS (CI) m/z 614 (MH+); [α]D25 -24° (c, 1.0, CHCl3). Anal. Calcd. for C34H44ClNO7 ·HCl: C, 62.77; H, 6.82; N, 2.15; Cl, 10.90. Found: C, 64.04; H, 8.24; N, 1.62; Cl, 8.99.

Provenance & Evidence