HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetamino-3-oxooctadecanoic acid → N-(1,3-dihydroxyoctadecan-2-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetamino-3-oxooctadecanoic acid | HCID 18625183 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | N-(1,3-dihydroxyoctadecan-2-yl)acetamide | HCID 2506 | — |
Reaction Steps
As shown below, the ester and ketone groups in an ester of 2-acetamino-3-oxooctadecanoic acid are reduced in the presence of lithium aluminium hydride (referred to as LAH) to obtain a racemate of 2-acetaminooctadecane-1,3-diol, as follows: ##STR7##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05916578 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-fc484f13a60d49f0b2093d8639ec0a45 |
| Source note | uspto-grants-1999_06 |