HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → Diethyl 2-((2-nitrophenylamino)methylene)malonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 2-Nitroaniline | HCID 6946 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Diethyl 2-((2-nitrophenylamino)methylene)malonate | HCID 225911 | 88% |
Reaction Steps
A mixture of 2-nitroaniline (41.4 g) and diethyl ethoxymethylenemalonate (66 ml) was heated on a steam bath for 24 hours. The hot reaction mixture was treated with ethanol (300 ml), cooled and filtered to give diethyl (2-nitroanilino)methylenemalonate in 88% yield, mp 104-105° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05916898 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-88b4073099294b0eb3064696cf2b0026 |
| Source note | uspto-grants-1999_06 |