HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → HCID 21250043, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 4-Fluoro-2-nitroaniline | HCID 67769 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 21250043 | HCID 21250043 | 45% |
Reaction Steps
Using an analogous procedure to that described in Example 2 in the section relating to the preparation of starting materials 4-fluoro-2-nitroaniline and diethyl ethoxymethylenemalonate were reacted, and then refluxed in diphenyl ether to give 3-ethoxycarbonyl-6-fluoro-8-nitro-4-oxo-3,4-dihydroquinoline in 45% yield, mp 278-280° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05916898 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-0fdc523737f44091bc8988b110e9275c |
| Source note | uspto-grants-1999_06 |