HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-[4-(2-Carboxy-2-methylpropyl)phenoxymethyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 67599519 | HCID 67599519 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-[4-(2-Carboxy-2-methylpropyl)phenoxymethyl]benzoic acid | HCID 67598632 | 91.7% |
Reaction Steps
A solution containing 30.2 g of potassium hydroxide in 150 ml 95% ethanol was added to 2-[4-(2-ethoxycarbonyl-2-methylpropyl)phenoxymethyl]benzoic acid ethyl ester (20.3 g) and warmed to reflux for 8 hours. The solution was cooled, diluted with water and adjusted to pH 5 with 6N HCl. Cooling overnight gave a precipitate which was collected and air dried to give 15.9 g of 2-[4-(2-carboxy-2-methylpropyl)phenoxymethyl]benzoic acid as a powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05917057 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-726318891d80418ba51d5228bfa4e519 |
| Source note | uspto-grants-1999_06 |