HCID 54434705, compound → HCID 178491886, compound

HRID 1417110Notes

Reaction equation

HRID 1417110 reaction equation
[NH2:1][C:2]1[C:7]([O:8][CH3:9])=[CH:6][C:5]([Cl:10])=[CH:4][C:3]=1[CH2:11][C:12]#[N:13]>C(O)(=O)C>[ClH:10].[Cl:10][C:5]1[CH:4]=[C:3]2[C:2](=[C:7]([O:8][CH3:9])[CH:6]=1)[NH:1][C:12](=[NH:13])[CH2:11]2

Participants

3

Reactant 1

HCID 54434705HCID 54434705, compound

Product 1

HCID 178491886HCID 178491886, compoundYield 126%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In accordance with Example No. 3, 15 g of (2-amino-5-chloro-3-methoxyphenyl)acetonitrile were brought to reflux in 150 ml of acetic acid. 11.2 g of 5-chloro-7-methoxy-1,3-dihydroindol-2-ylideneamine hydrochloride were obtained (yield=63.6%).

Sources & evidence

ORD record
ord-3ba1f6f0d0ae4ee384d0def462887d51
Source dataset
uspto-grants-1999_03
Patent number
US05876465

Reaction notes

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