Ethyl 3-ethoxy-3-iminopropionate hydrochloride → HCID 54211963, compound

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N-[3-nitro-4-(3-ethoxy-5-pyrazolon-1-yl)phenyl]2- [4-(4-hydroxyphenylsulphonyl)phenoxy]undecylamide was prepared by the method in (2b) from N-(4-hydrazino-3-nitrophenyl)- 2-[4-(4-hydroxyphenylsulphonyl)phenoxy]undecylamide (3b) and O-ethyl 2-ethoxycarbonylacetimidate hydrochloride (prepared from ethyl cyanoacetate and ethanol as in method (2a)). The crude product was partially purified by column chromatography using 63-200 mesh silica gel and ethyl acetate/60°-80° C. petroleum ether (1:1) as the eluent. The yield was 29% over the two stages (3a) to (3c).

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