HCID 178483585, compound → HCID 67598383, compound

Participants

Reaction Conditions

Reaction Steps

1,7-bis(N,N-dimethylamino)-1,6-heptadien-3,4,5-trione 4-(2,4-dichlorophenyl)hydrazone (2.10 g) was dissolved in dry dichloromethane (6 ml), silica gel (19 g) was added and solvent was removed in vacuo. The mixture was heated at 80° C. for 30 minutes and then at 120° C. for 2 hours. After cooling, the product was extracted with acetone and the acetone was removed in vacuo. The oily residue was solidified with diethyl ether to afford 1-(2,4-dichlorophenyl)-3-[3-(N,N-dimethylamino)-1-oxo-2-propenyl]4(1H)-pyridazi- none (1.40 g), m.p. 152°-154° C.

Provenance & Evidence