Methanesulfonate → HCID 53682799, compound

Participants

Reaction Steps

Compound 38 (450 mg, 0.47 mmol) was converted into its 6-O-methane sulfonyl derivative exactly as described for the preparation of 10 to provide 39 (385 mg, 79.1%) as a syrup after chromatography on silica gel using (hexane:ethyl acetate; 2:1) as eluant; ›α!D +36.1° (c 0.95, chloroform). 1H-n.m.r. (CDCl3): δ 4.99(d, 1H, J1',2' 3.8 Hz, H-1'), 4.96(d, 1H, J1,2 3.8 Hz, H-1), 3.58(s, 3H, OCH3), 2.93(s, 3H, CH3SO2), 2.39(d, 1H, J 3.2 Hz, OH, D2O exchangeable), 2.21(t, 2H, J 7.5 Hz, CH2COO).

Provenance & Evidence