(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propanoic acid → HCID 11061479, compound

HRID 1417183Notes

Reaction equation

HRID 1417183 reaction equation
C(O)(=O)C(O)=O.[C:7]([O:11][C:12](=[O:33])[CH2:13][N:14]1[CH2:19][CH2:18][NH:17][C@@H:16]([CH2:20][CH2:21][CH2:22][CH2:23][NH:24][C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[C:15]1=[O:32])([CH3:10])([CH3:9])[CH3:8].[NH:34]([C:48]([O:50][CH2:51][C:52]1[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=1)=[O:49])[C@H:35]([C:45](O)=[O:46])[CH2:36][C:37]1[CH:42]=[CH:41][C:40]([O:43][CH3:44])=[CH:39][CH:38]=1>>[C:7]([O:11][C:12](=[O:33])[CH2:13][N:14]1[CH2:19][CH2:18][N:17]([C:45](=[O:46])[C@@H:35]([NH:34][C:48]([O:50][CH2:51][C:52]2[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=2)=[O:49])[CH2:36][C:37]2[CH:38]=[CH:39][C:40]([O:43][CH3:44])=[CH:41][CH:42]=2)[C@@H:16]([CH2:20][CH2:21][CH2:22][CH2:23][NH:24][C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[C:15]1=[O:32])([CH3:10])([CH3:8])[CH3:9]

Participants

3

Reactant 2

HCID 10496574(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propanoic acidHCID 70045923HCID 70045923, compound

Product 1

HCID 11061479HCID 11061479, compound

Procedure

In substantially the same manner as in Reference Example 2, the title compound was synthesized using (S)-3-(4-t-butoxycarbonylaminobutyl)-2-oxopiperazine-1-acetic acid t-butyl ester oxalate and N-Z-Tyr(OMe)-OH.

Sources & evidence

ORD record
ord-9d58bc1121e844d68634eaf66d50a93d
Source dataset
uspto-grants-1999_03
Patent number
US05876756

Reaction notes

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