Hydrazine → HCID 67598281, compound

Participants

Reaction Steps

5.0 g of 4-methyl-N-[4-(4-nitrophenoxy)-butyl]benzenesulfonamide (Example 35) is dissolved in 500 ml of ethanol, 1.5 ml of anhydrous hydrazine and 500 mg of 10% palladium on carbon are added, and the mixture is then stirred under reflux for four hours. The reaction mixture is filtered hot. Cooling the filtrate to room temperature produces a precipitate, which is collected. The filtrate is reheated to boiling and utilized to re-extract the palladium-carbon residue, and after filtration, cooled to room temperature, the precipitate being collected. The process is repeated until no further precipitate is formed on cooling to room temperature. After drying at 60° in vacuo, the combined precipitates weigh 3.3 g; m.p. 176°-178° C.

Provenance & Evidence