反应详情

A suspension of 13.5 g of 2-[4-(4-acetyl-phenoxy)butyl]-1H-isoindole-1,3(2H)-dione in 500 ml of ethanol is treated with 1.4 ml of anhydrous hydrazine, and the mixture stirred at reflux for 9 hours. After cooling to room temperature, the precipitate is collected. Concentration of the filtrate gives the crude title compound, which is used directly for further synthesis.

1. temperatureat reflux for 9 hours
2. customthe precipitate is collected