Dichloromethane → 4-Chloro-3-{5-methyl-3-[3-(4-methyl-piperazine-1-sulfonyl)-phenylamino]-benzo[1,2,4]triazin-7-yl}-phenol

HRID 141741Notes

Reaction equation

HRID 141741 reaction equation
[B:38]([Br:39])([Br:40])[Br:41].[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[c:13]([n:14][c:15]([NH:18][c:19]4[cH:20][c:21]([S:25](=[O:26])(=[O:27])[N:28]5[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]5)[cH:22][cH:23][cH:24]4)[n:16][n:17]3)[c:35]([CH3:37])[cH:36]2)[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[Cl:42][CH2:43][Cl:44]>>[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[c:13]([n:14][c:15]([NH:18][c:19]4[cH:20][c:21]([S:25](=[O:26])(=[O:27])[N:28]5[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]5)[cH:22][cH:23][cH:24]4)[n:16][n:17]3)[c:35]([CH3:37])[cH:36]2)[cH:4][c:5]([OH:8])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 59837628[7-(2-Chloro-5-methoxy-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[3-(4-methyl-piperazine-1-sulfonyl)-phenyl]-amine

Product 1

HCID 116350474-Chloro-3-{5-methyl-3-[3-(4-methyl-piperazine-1-sulfonyl)-phenylamino]-benzo[1,2,4]triazin-7-yl}-phenol

Sources & evidence

ORD record
ord-246fd7c7034d4b64a7b5eacfa2096022
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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