4-Phenylbenzyl chloride → 1-(4-Phenylbenzyl)-4-cyanoindole

HRID 1417489Notes

Reaction equation

[C:1]([C:3]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:4]=1[CH:5]=[CH:6][NH:7]2)#[N:2].[C:12]1([C:18]2[CH:25]=[CH:24][C:21]([CH2:22]Cl)=[CH:20][CH:19]=2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:12]1([C:18]2[CH:19]=[CH:20][C:21]([CH2:22][N:7]3[C:8]4[C:4](=[C:3]([C:1]#[N:2])[CH:11]=[CH:10][CH:9]=4)[CH:5]=[CH:6]3)=[CH:24][CH:25]=2)[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 154634-Phenylbenzyl chloride

HCID 38176024-Cyanoindole

Product 1

HCID 545552881-(4-Phenylbenzyl)-4-cyanoindole

Procedure

Following a procedure and using relative proportions of starting materials similar to those described in Example 65, but using 4-cyanoindole and 4-phenylbenzylchloride as starting materials, the title compound was obtained as a solid.

Sources & evidence

ORD record: ord-2c1fdb461ea043fea384dee1fbbd26d5
Source dataset: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05877199

Reaction notes

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