(3-Bromopropyl)benzene → tert-Butyl [4-Methyl-1-methylthio-9-(3-phenylpropyl)carbazol-2-yl]acetate

HRID 1417504Notes

Reaction equation

HRID 1417504 reaction equation
[CH3:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=1.[C:25]1([CH2:31][CH2:32][CH2:33]Br)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH3:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:7]([CH2:33][CH2:32][CH2:31][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:6]=2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=1

Participants

3

Reactant 2

HCID 12503(3-Bromopropyl)benzeneHCID 54527372Tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate

Product 1

HCID 67571952tert-Butyl [4-Methyl-1-methylthio-9-(3-phenylpropyl)carbazol-2-yl]acetateYield 74%

Procedure

Following a procedure and using relative proportions of starting materials similar to those described in Example 4, but using tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate and 3-phenylpropyl bromide as starting materials, the title compound was obtained in a yield of 74% as an oil.

Sources & evidence

ORD record
ord-0565f1d8e19943cbab33c4d2a7944035
Source dataset
uspto-grants-1999_03
Patent number
US05877199

Reaction notes

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