1-(2-Bromoethyl)-3-chlorobenzene → HCID 86753778, compound

HRID 1417510Notes

Reaction equation

HRID 1417510 reaction equation
[CH3:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=1.[Cl:25][C:26]1[CH:27]=[C:28]([CH2:32][CH2:33]Br)[CH:29]=[CH:30][CH:31]=1>>[Cl:25][C:26]1[CH:27]=[C:28]([CH2:32][CH2:33][N:7]2[C:6]3[C:5]([S:15][CH3:16])=[C:4]([CH2:17][C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH:3]=[C:2]([CH3:1])[C:14]=3[C:13]3[C:8]2=[CH:9][CH:10]=[CH:11][CH:12]=3)[CH:29]=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 1401401-(2-Bromoethyl)-3-chlorobenzeneHCID 54527372Tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate

Product 1

HCID 86753778HCID 86753778, compoundYield 73%

Procedure

Following a procedure and using relative proportions of starting materials similar to those described in Example 4, but using tert-butyl (4-methyl-1-methylthiocarbazol-2-yl)acetate and 2-(3-chlorophenyl)ethyl bromide as starting materials, the title compound was obtained in a yield of 73% as an oil.

Sources & evidence

ORD record
ord-37d19b3fe6d64e18b192e89118c90a99
Source dataset
uspto-grants-1999_03
Patent number
US05877199

Reaction notes

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