Benzoyl chloride → HCID 286389, compound

HRID 1417568Notes

Reaction equation

HRID 1417568 reaction equation
[NH2:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[C:11](Cl)(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:11]([NH:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1)(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 123445(+-)-1-Aminoindan

Product 1

HCID 286389HCID 286389, compound

Procedure

The title compound was prepared in 77% from (rac)-1-aminoindan (1.0 g, 7.5 mmole) and benzoyl chloride (2.1 g, 15 mmole), under the Schotten-Bauman conditions, according to J.Chem.Soc. 71, 251 (1897) and J.Org.Chem. 27, 4465 (1962), m.p.: 140°-2° C.

Sources & evidence

ORD record
ord-8e5cc84fa147411c84d5dc2dfebd2518
Source dataset
uspto-grants-1999_03
Patent number
US05877221

Reaction notes

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