HCID 86753812, compound → HCID 86753814, compound

Participants

Reaction Steps

To the above Compound (41a) (35 mg, 0.095 mmol) dissolved in 5 ml of methanol was added 7 mg of 10% palladium-carbon, and the mixture stirred under hydrogen atmosphere for 7.5 hours at room temperature. After removing palladium-carbon by filtration, the filtrate was concentrated under reduced pressure. The residue was purified by a preparative thin layer chromatography (Merck, Kieselgel 60 F254, 0.5 mm; chloroform:methanol 15:1) to give 30 mg (85%) of Compound (42).

Provenance & Evidence