HCID 15860250, compound → HCID 10624435, compound

Participants

Reaction Steps

A solution comprising about 210 mg of compound 5a (m=6) in about 6 ml of EtOAc and about 2 ml of ethanol (EtOH, 2 ml) was stirred over about 40 mg of platinum (IV) oxide (PtO2) under an atmosphere of hydrogen for 2.5 h. The catalyst was removed by filtration and the filtrate concentrated. The residue was purified by silica gel chromatography (Petroleum ether: EtOAc, 1:1), yielding pure compound 6a (201 mg, 95.3%).

Provenance & Evidence