Hydrochloric Acid → HCID 15342534, compound

Participants

Reaction Steps

460 mg of 5-benzyloxy-4-methoxymethyl-9-{2-[N-methyl-N-benzyl-amino]-2-oxoethyl}-9H-pyrido[3,4-b]indole-3-carboxylic acid-(1-methylethyl)-ester is mixed in 3 ml of methanol with 1 ml of aqueous 2N sodium hydroxide solution and held at 40° C. until the reaction is completed. Then, the reaction mixture is acidified with dilute hydrochloric acid, the precipitated reaction product is suctioned off, washed with water and diethyl ether and dried in a vacuum. 370 mg of 5-benzyloxy-4-methoxymethyl-9-{2-[N-methyl-N-benzyl-amino]-2-oxoethyl}-9H-pyrido-[3,4-b]indole-3-carboxylic acid (decomposition starting at 239°) is obtained.

Provenance & Evidence