反应详情

Using an analogous reaction procedure to that described in Example 6, 6-chloro-4-(3'-chloro-4'-fluoroanilino)pyrimidine (0.258 g) was reacted with 4-[N-(2-hydroxyethyl)-N-methylamino]aniline (0.166 g). The product so obtained was recrystallised from a mixture of methylene chloride, methanol and hexane to give 4-[3'-chloro-4'-fluoroanilino]6-[4'-{N-(2-hydroxyethyl) -N-methylamino}anilino]pyrimidine in 10% yield;

1. customan analogous reaction procedure to
2. customThe product so obtained
3. customwas recrystallised from a mixture of methylene chloride, methanol and hexane