3-[(Thien-2-yl)methylene]-2-indolinone → HCID 406226, compound
Reaction equation
[N+]([C:4]1[CH:20]=[CH:19][C:7]([CH:8]=[C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[NH:11][C:10]2=[O:18])=[CH:6][CH:5]=1)([O-])=O.FC1C=CC(C=C2C3C(=CC=CC=3)N[C:28]2=[O:36])=CC=1.FC(F)(F)C1C=CC(C=C2C3C(=CC=CC=3)N[C:47]2=[O:55])=CC=1.S1C=CC=C1C=C1C2C(=CC=CC=2)NC1=O>>[CH3:47][O:55][C:19]1[CH:20]=[CH:4][C:5]([O:36][CH3:28])=[CH:6][C:7]=1[CH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[NH:11][C:10]1=[O:18]Participants
5
Procedure
3-(4-Nitrobenzylidene)-2-indolinone, 3-(4-Fluorobenzylidene)-2-indolinone, 3-(4-Trifluoromethylbenzylidene)-2-indolinone, and 3-[(Thien-2-yl)methylene]-2-indolinone may also be synthesized according to the above protocol.
Sources & evidence
- ORD record
- ord-9abc5646b80545079fc4871c14335aa7
- Source dataset
- uspto-grants-1999_03
- Patent number
- US05880141
Reaction notes
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