HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15370446, compound → methyl (2S)-1-[(1S)-1-phenylethyl]azetidine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15370446 | HCID 15370446 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | methyl (2S)-1-[(1S)-1-phenylethyl]azetidine-2-carboxylate | HCID 10998528 | — |
| Product | HCID 11790692 | HCID 11790692 | — |
Reaction Steps
The obtained methyl N-[(S)-methylbenzyl]azetidine-2-(RS)-carboxylate (10 g) was subjected to silica gel column chromatography (eluate: hexane/ethyl acetate=10/1) to give methyl N-[(S)-methylbenzyl]azetidine-2-(S)-carboxylate (4.8 g) and methyl N-[(S)-methylbenzyl]azetidine-2-(R)-carboxylate (4.68 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05880291 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-cbc9dafe61be4e3e8c5b60fc2f6a4c3c |
| Source note | uspto-grants-1999_03 |