HCID 19348674, compound → Methyl 3-(4-hydroxy-2-methoxyphenyl)heptanoate

HRID 1418218Notes

Reaction equation

HRID 1418218 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9]C)[CH:6]=[CH:5][C:4]=1[CH:11]([CH2:17][CH2:18][CH2:19][CH2:20]C)[CH2:12][C:13]([O:15][CH3:16])=[O:14].C(OC1C=CC(C(CCCC)CC(O)=O)=C(OC)C=1)C1C=CC=CC=1>>[OH:9][C:7]1[CH:6]=[CH:5][C:4]([CH:11]([CH2:17][CH2:18][CH2:19][CH3:20])[CH2:12][C:13]([O:15][CH3:16])=[O:14])=[C:3]([O:2][CH3:1])[CH:8]=1

Participants

3

Reactant 2

HCID 19348674HCID 19348674, compoundHCID 193488263-(4-Benzyloxy-2-methoxyphenyl)heptanoic acid

Product 1

HCID 19348616Methyl 3-(4-hydroxy-2-methoxyphenyl)heptanoate

Procedure

Following a similar procedure to that described in Preparation 32(i), but using 3-(4-benzyloxy-2-methoxyphenyl)heptanoic acid prepared as described in Preparation 30G), the corresponding methyl ester derivative was obtained. Hydrogenolysis of this derivative and subsequent treatment of the reaction mixture were conducted in a similar manner to that described in Example 124 to give the title compound as an oily substance.

Workup

  1. customprepared
  2. customwas obtained

Sources & evidence

ORD record
ord-825c6c75461e4e0e966e22a9a15ebf9b
Source dataset
uspto-grants-1999_03
Patent number
US05880147

Reaction notes

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