HCID 19348572, compound → HCID 19348450, compound

HRID 1418233Notes

Reaction equation

HRID 1418233 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][C:13]([O:15]CC)=[O:14])=[CH:7][C:6]=1[NH:18][C:19](=[O:37])[CH2:20][CH:21]([C:27]1[C:32]([O:33][CH3:34])=[CH:31][CH:30]=[CH:29][C:28]=1[O:35][CH3:36])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])([CH3:4])([CH3:3])[CH3:2]>C(Cl)Cl.CCCCCC>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[CH:7][C:6]=1[NH:18][C:19](=[O:37])[CH2:20][CH:21]([C:27]1[C:28]([O:35][CH3:36])=[CH:29][CH:30]=[CH:31][C:32]=1[O:33][CH3:34])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 1

HCID 19348572HCID 19348572, compound

Product 1

HCID 19348450HCID 19348450, compound

Reagents, catalysts & solvents 1

HCID 21226440Methylenechloride HexaneSolvent

Procedure

Following a similar procedure to that described in Preparation 77, but using N-[2-t-butyl-5-(2-carboethoxyethyl)phenyl]-3-(2,6-dimethoxyphenyl)octanamide (prepared as described in Preparation 86), the title compound was obtained as colorless crystals, melting at 52°-53° C. (from methylene chloride-hexane).

Workup

  1. customthat described in Preparation 77

Sources & evidence

ORD record
ord-0f155ef49697444fa33239556a746f85
Source dataset
uspto-grants-1999_03
Patent number
US05880147

Reaction notes

Loading…