HCID 86753870, compound → HCID 54282651, compound

HRID 1418258Notes

Reaction equation

HRID 1418258 reaction equation
[I:1][C:2]1[C:7]([CH2:8][CH:9]=[CH:10][OH:11])=[C:6]([I:12])[C:5]([CH2:13][CH:14]=[CH:15][OH:16])=[C:4]([I:17])[C:3]=1[CH2:18][CH:19]=[CH:20][OH:21]>N1C=CC=CC=1.C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]([CH2:18][CH:19]=[CH:20][O:21][C:10](=[O:11])[CH3:9])=[C:4]([I:17])[C:5]([CH2:13][CH:14]=[CH:15][O:16][C:15](=[O:16])[CH3:14])=[C:6]([I:12])[C:7]=1[CH2:8][CH:9]=[CH:10][O:11][C:20](=[O:21])[CH3:19]

Participants

4

Reactant 1

HCID 86753870HCID 86753870, compound

Product 1

HCID 54282651HCID 54282651, compound

Reagents, catalysts & solvents 2

HCID 1049PyridineSolventHCID 7918Acetic AnhydrideSolvent

Procedure

1,3,5-Triiodo-2,4,6-tris(1-hydroxyprop-en-3-yl)benzene (560 mg, 0.90 mmol) was dissolved in a mixture of pyridine (8 ml) and acetic anhydride (8 ml). After stirring at ambient temperature for 16 hours, the solvent was evaporated and the residue was purified by preparative HPLC (RP-18, CH3CN: H2O 80:20). Yield 310 mg (46%).

Workup

  1. customthe solvent was evaporated
  2. customthe residue was purified by preparative HPLC (RP-18, CH3CN: H2O 80:20)

Sources & evidence

ORD record
ord-0a4efdc960524e6a8e1562f93f34c1ea
Source dataset
uspto-grants-1999_03
Patent number
US05882628

Reaction notes

Loading…