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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1418335Generated: October 26, 2026

1-Phenylpiperazine → 4-t-butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(4-phenylpiperazinyl)-4-pyrimidinyl]benzenesulfonamide

https://huagongshe.com/reaction/1418335

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PhenylpiperazineHCID 7096—
Reactant4-t-butyl-N-[2,6-dichloro-5-(2-methoxyphenoxy)-4-pyrimidinyl]benzenesulfonamideHCID 86753872—
Product4-t-butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(4-phenylpiperazinyl)-4-pyrimidinyl]benzenesulfonamideHCID 86753873—

Reaction Steps

The procedure described in Synthesis Example 2 was repeated by use of 4-t-butyl-N-[2,6-dichloro-5-(2-methoxyphenoxy)-4-pyrimidinyl]benzenesulfonamide (5) and 1-phenylpiperazine, to thereby obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05883092
Source datasetuspto-grants-1999_03
ORD IDord-67970708c0034f95b76b2a7363a8fb5a
Source noteuspto-grants-1999_03