2-Isopropylaniline → HCID 54380580, compound

HRID 1418337Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][N:24]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)[CH2:23][CH2:22]3)[N:18]=[C:17]([O:33][CH2:34][CH2:35][C:36]([OH:38])=O)[C:16]=2[O:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][C:41]=2[O:46][CH3:47])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:48]([C:51]1[CH:57]=[CH:56][CH:55]=[CH:54][C:52]=1[NH2:53])([CH3:50])[CH3:49]>>[CH:48]([C:51]1[CH:57]=[CH:56][CH:55]=[CH:54][C:52]=1[NH:53][C:36](=[O:38])[CH2:35][CH2:34][O:33][C:17]1[C:16]([O:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][C:41]=2[O:46][CH3:47])=[C:15]([NH:14][S:11]([C:8]2[CH:7]=[CH:6][C:5]([C:1]([CH3:2])([CH3:4])[CH3:3])=[CH:10][CH:9]=2)(=[O:13])=[O:12])[N:20]=[C:19]([N:21]2[CH2:26][CH2:25][N:24]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH2:23][CH2:22]2)[N:18]=1)([CH3:50])[CH3:49]

Participants

Reactant 2

HCID 125612-Isopropylaniline

HCID 54073876HCID 54073876, compound

Product 1

HCID 54380580HCID 54380580, compound

Procedure

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-(4-phenylpiperazinyl)-4-pyrimidinyloxy]propionic acid and 2-isopropylaniline, to thereby obtain the title compound as a pale yellow oil.

Sources & evidence

ORD record: ord-d57eb5deba3e481986a14495347c5842
Source dataset: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05883092

Reaction notes

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