HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Isopropylpiperazine → 4-t-butyl-N-[6-chloro-2-(4-isopropylpiperazinyl)-5-(2-methoxyphenoxy)-4-pyrimidinyl]-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Isopropylpiperazine | HCID 78013 | — |
| Reactant | 4-t-butyl-N-[2,6-dichloro-5-(2-methoxyphenoxy)-4-pyrimidinyl]benzenesulfonamide | HCID 86753872 | — |
| Product | 4-t-butyl-N-[6-chloro-2-(4-isopropylpiperazinyl)-5-(2-methoxyphenoxy)-4-pyrimidinyl]-benzenesulfonamide | HCID 86753874 | — |
Reaction Steps
The procedure described in Synthesis Example 2 was repeated by use of 4-t-butyl-N-[2,6-dichloro-5-(2-methoxyphenoxy)-4-pyrimidinyl]benzenesulfonamide (5) and 1-isopropylpiperazine, to thereby obtain the title compound as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05883092 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-f181168146f34563a514280460f6f955 |
| Source note | uspto-grants-1999_03 |