2-Isopropylaniline → HCID 53632862, compound

HRID 1418341Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][N:24]([CH3:27])[CH2:23][CH2:22]3)[N:18]=[C:17]([O:28][CH2:29][CH2:30][C:31]([OH:33])=O)[C:16]=2[O:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][C:36]=2[O:41][CH3:42])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:43]([C:46]1[CH:52]=[CH:51][CH:50]=[CH:49][C:47]=1[NH2:48])([CH3:45])[CH3:44]>>[CH:43]([C:46]1[CH:52]=[CH:51][CH:50]=[CH:49][C:47]=1[NH:48][C:31](=[O:33])[CH2:30][CH2:29][O:28][C:17]1[C:16]([O:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][C:36]=2[O:41][CH3:42])=[C:15]([NH:14][S:11]([C:8]2[CH:7]=[CH:6][C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])=[CH:10][CH:9]=2)(=[O:12])=[O:13])[N:20]=[C:19]([N:21]2[CH2:26][CH2:25][N:24]([CH3:27])[CH2:23][CH2:22]2)[N:18]=1)([CH3:45])[CH3:44]

Participants

Reactant 2

HCID 125612-Isopropylaniline

HCID 54365078HCID 54365078, compound

Product 1

HCID 53632862HCID 53632862, compound

Procedure

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-(4-methylpiperazinyl)-4-pyrimidinyloxy]propionic acid and 2-isopropylaniline, to thereby obtain the title compound as a pale yellow solid.

Sources & evidence

ORD record: ord-010f6bcade2840bd88fc5f8da965dccf
Source dataset: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05883092

Reaction notes

Loading…