2-Isopropylaniline → HCID 44213937, compound

HRID 1418347Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][N:24]([CH:27]=[O:28])[CH2:23][CH2:22]3)[N:18]=[C:17]([O:29][CH2:30][CH2:31][C:32]([OH:34])=O)[C:16]=2[O:35][C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][C:37]=2[O:42][CH3:43])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:44]([C:47]1[CH:53]=[CH:52][CH:51]=[CH:50][C:48]=1[NH2:49])([CH3:46])[CH3:45]>>[CH:44]([C:47]1[CH:53]=[CH:52][CH:51]=[CH:50][C:48]=1[NH:49][C:32](=[O:34])[CH2:31][CH2:30][O:29][C:17]1[C:16]([O:35][C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][C:37]=2[O:42][CH3:43])=[C:15]([NH:14][S:11]([C:8]2[CH:9]=[CH:10][C:5]([C:1]([CH3:3])([CH3:4])[CH3:2])=[CH:6][CH:7]=2)(=[O:12])=[O:13])[N:20]=[C:19]([N:21]2[CH2:22][CH2:23][N:24]([CH:27]=[O:28])[CH2:25][CH2:26]2)[N:18]=1)([CH3:46])[CH3:45]

Participants

Reactant 2

HCID 125612-Isopropylaniline

HCID 54262869HCID 54262869, compound

Product 1

HCID 44213937HCID 44213937, compound

Procedure

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-2-(4-formylpiperazinyl)-5-(2-methoxyphenoxy)-4-pyrimidinyloxy]propionic acid and 2-isopropylaniline, to thereby obtain the title compound as a colorless solid.

Sources & evidence

ORD record: ord-eccb90ed3e72440bb5f26050f2392682
Source dataset: uspto-grants-1999_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05883092

Reaction notes

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