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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1418350Generated: November 3, 2026

2-Ethylaniline → N-(2-ethylphenyl)-3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionamide

https://huagongshe.com/reaction/1418350

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-EthylanilineHCID 11357—
Reactant3-[6-(4-t-Butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionic acidHCID 15381103—
ProductN-(2-ethylphenyl)-3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionamideHCID 53805295—

Reaction Steps

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionic acid and 2-ethylaniline, to thereby obtain the title compound as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05883092
Source datasetuspto-grants-1999_03
ORD IDord-836a81e2b24041dc88201f0a8f8a641e
Source noteuspto-grants-1999_03