3-Isopropylaniline → HCID 53988400, compound

HRID 1418354Notes

Reaction equation

HRID 1418354 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)[N:18]=[C:17]([O:27][CH2:28][CH2:29][C:30]([OH:32])=O)[C:16]=2[O:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=2[O:40][CH3:41])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:42]([C:45]1[CH:46]=[C:47]([CH:49]=[CH:50][CH:51]=1)[NH2:48])([CH3:44])[CH3:43]>>[CH:42]([C:45]1[CH:46]=[C:47]([NH:48][C:30](=[O:32])[CH2:29][CH2:28][O:27][C:17]2[C:16]([O:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[O:40][CH3:41])=[C:15]([NH:14][S:11]([C:8]3[CH:7]=[CH:6][C:5]([C:1]([CH3:2])([CH3:4])[CH3:3])=[CH:10][CH:9]=3)(=[O:13])=[O:12])[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)[N:18]=2)[CH:49]=[CH:50][CH:51]=1)([CH3:44])[CH3:43]

Participants

3

Reactant 2

HCID 4586793-IsopropylanilineHCID 153811033-[6-(4-t-Butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionic acid

Product 1

HCID 53988400HCID 53988400, compound

Procedure

The procedure described in Example 2 was repeated by use of 3-[6-(4-t-butylphenylsulfonylamino)-5-(2-methoxyphenoxy)-2-morpholino-4-pyrimidinyloxy]propionic acid and 3-isopropylaniline, to thereby obtain the title compound as a colorless oil.

Sources & evidence

ORD record
ord-b9472eab2ece4cd597aa35e37fee5bc5
Source dataset
uspto-grants-1999_03
Patent number
US05883092

Reaction notes

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