HCID 35370604, compound → HCID 67569749, compound

HRID 1418382Notes

Reaction equation

HRID 1418382 reaction equation
[ClH:1].Cl.[NH2:3][C:4]1[C:12]([F:13])=[CH:11][CH:10]=[C:9]([F:14])[C:5]=1[C:6]([NH2:8])=[NH:7].C1O[C:18]2([CH2:23][CH2:22][N:21]([C:24](=[O:33])[C:25]3[CH:30]=[CH:29][C:28]([C:31]#[N:32])=[CH:27][CH:26]=3)[CH2:20][CH2:19]2)OC1>>[ClH:1].[C:31]([C:28]1[CH:27]=[CH:26][C:25]([C:24]([N:21]2[CH2:22][CH2:23][C:18]3([N:7]=[C:6]([NH2:8])[C:5]4[C:4](=[C:12]([F:13])[CH:11]=[CH:10][C:9]=4[F:14])[NH:3]3)[CH2:19][CH2:20]2)=[O:33])=[CH:30][CH:29]=1)#[N:32]

Participants

3

Reactant 2

HCID 35370604HCID 35370604, compoundHCID 67568295HCID 67568295, compound

Product 1

HCID 67569749HCID 67569749, compound

Procedure

This was prepared with 2-amino-3,6-difluorobenzamidine dihydrochloride (Example G) and 1-(4-cyanobenzoyl)-4-piperidone ethylene ketal by the method of Example 1 to give the title compound as a yellow solid, m.p >270° C., MS (+CI) 382 ([M+H]+).

Sources & evidence

ORD record
ord-b9a8dc1056c647b08752c9d442eef7a0
Source dataset
uspto-grants-1999_03
Patent number
US05883102

Reaction notes

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