HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bis(2-chloroethyl) ether → Ethyl 1-(3-benzyloxy-5-fluorophenyl)cyclopentane-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bis(2-chloroethyl) ether | HCID 8115 | — |
| Reactant | ethyl 4-(3-benzyloxy-5-fluorophenyl)-3,4,5,6-tetrahydro-2H-pyran-4-carboxylate | HCID 18786326 | — |
| Reactant | Ethyl 3-benzyloxy-5-fluorophenylacetate | HCID 18786372 | — |
| Product | Ethyl 1-(3-benzyloxy-5-fluorophenyl)cyclopentane-1-carboxylate | HCID 18786354 | — |
Reaction Steps
The titled compound was prepared from ethyl 3-benzyloxy-5-fluorophenylacetate according to the preparation of ethyl 4-(3-benzyloxy-5-fluorophenyl)-3,4,5,6-tetrahydro-2H-pyran-4-carboxylate except substituting 1,4-dibromobutane for bis-(2-chloroethyl) ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05883106 |
| Source dataset | uspto-grants-1999_03 |
| ORD ID | ord-8859454804ad4ed4a891c3587f8db4a3 |
| Source note | uspto-grants-1999_03 |