Thionyl Chloride → 4-(2-Methylimidazol-1-yl)benzyl chloride hydrochloride

Participants

Reaction Steps

4-(2-Methylimidazol-1-yl)benzyl alcohol (1.28 g, 6.8 mmol) in SOCl2 (5 ml) was stirred at ambient temperature for 30 minutes and then volatiles removed under reduced pressure. The resultant crude product was washed with minimal dry Et2O and dried in vacuo to afford the titled compound (1.65 g, quant.) as white solids.

Provenance & Evidence