HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran → 4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran | HCID 11287160 | — |
| Edukt | 1-(4-Chloromethylphenyl)-2-methyl-1H-imidazole | HCID 14998821 | — |
| Produkt | 4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran | HCID 11349311 | 38% |
Reaktionsschritte
4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran was reacted with 4-(2-methylimidazol-1-yl)benzylchloride to give the titled compound in 38% yield as colorless needles according to the procedure described in Example 2H.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05883106 |
| Quelldatensatz | uspto-grants-1999_03 |
| ORD ID | ord-b4274353fdeb485aa342c7369e3dbcc5 |
| Quellennotiz | uspto-grants-1999_03 |