HCID 67587170, compound → HCID 67568975, compound

HRID 1418598Notes

Reaction equation

HRID 1418598 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([S:7][C:8]2[CH:13]=[CH:12][C:11](/[CH:14]=[C:15](\[CH3:19])/[C:16]([OH:18])=[O:17])=[CH:10][C:9]=2[C:20]([F:23])([F:22])[F:21])=[CH:3][CH:2]=1.S[C:25]1C=CN=C[CH:26]=1>>[N:1]1[CH:6]=[CH:5][C:4]([S:7][C:8]2[CH:13]=[CH:12][C:11](/[CH:14]=[C:15](\[CH3:19])/[C:16]([O:18][CH2:25][CH3:26])=[O:17])=[CH:10][C:9]=2[C:20]([F:21])([F:23])[F:22])=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 67587170HCID 67587170, compoundHCID 178418431pyridine-4-thiol

Product 1

HCID 67568975HCID 67568975, compound

Procedure

E-3-[4-(4-Pyridylthio)-3-(trifluoromethyl)phenyl]-2-methyl-propenoic acid guanidide dihydrochloride ##STR9## 4 a) The ester from 3 a was reacted with 4-mercaptopyridine analogously to 3 b. Ethyl E-3-[4-(4-pyridylthio)-3-(trifluoromethyl)phenyl]-2-methyl-propenoate was isolated.

Sources & evidence

ORD record
ord-f80c86566e494ff8a96e0e1bb6d16b45
Source dataset
uspto-grants-1999_03
Patent number
US05883133

Reaction notes

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