2,4,6-Trifluorobenzaldehyde → HCID 67568187, compound

HRID 1418600Notes

Reaction equation

HRID 1418600 reaction equation
[F:1][C:2]1[CH:7]=[C:6](OC2C=CC=C(N(C)C)C=2)[CH:5]=[C:4]([F:18])[C:3]=1/[CH:19]=[C:20](\[CH3:24])/[C:21]([OH:23])=[O:22].F[C:26]1C=C(F)C=C(OC2C=CC=C(N(C)C)C=2)[C:27]=1/C=C(\C)/C(O)=O.[F:49]C1C=C(F)C=C(F)C=1C=O>>[F:18][C:4]1[CH:5]=[C:6]([F:49])[CH:7]=[C:2]([F:1])[C:3]=1/[CH:19]=[C:20](\[CH3:24])/[C:21]([O:23][CH2:26][CH3:27])=[O:22]

Participants

4

Reactant 3

HCID 5218452,4,6-TrifluorobenzaldehydeHCID 67586476HCID 67586476, compoundHCID 67587604HCID 67587604, compound

Product 1

HCID 67568187HCID 67568187, compound

Procedure

E-3-[2,6-Difluoro-4-(3-dimethylaminophenoxy)phenyl]-2-methyl-propenoic acid guanidide and E-3-[2,4-difluoro-6-(3-dimethylaminophenoxy)-phenyl]-2-methyl-propenoic acid guanidide ##STR16## 11 a/12 a) Ethyl E-3-[2,4,6-trifluorophenyl]-2-methyl-propenoate was synthesized analogously to 8 a starting from 2,4,6-trifluorobenzaldehyde.

Sources & evidence

ORD record
ord-dff2361cfa18486796cea1b20d194dff
Source dataset
uspto-grants-1999_03
Patent number
US05883133

Reaction notes

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